A nanoporous gold membrane for sensing applications
A nanoporous gold membrane for sensing applications
Design and fabrication of three-dimensionally structured, gold membranes containing hexagonally close-packed microcavities with nanopores in the base, are described. Our aim is to create a nanoporous structure with localized enhancement of the fluorescence or Raman scattering at, and in the nanopore when excited with light of approximately 600 nm, with a view to provide sensitive detection of biomolecules. A range of geometries of the nanopore integrated into hexagonally close-packed assemblies of gold micro-cavities was first evaluated theoretically. The optimal size and shape of the nanopore in a single microcavity were then considered to provide the highest localized plasmon enhancement (of fluorescence or Raman scattering) at the very center of the nanopore for a bioanalyte traversing through. The optimized design was established to be a 1200 nm diameter cavity of 600 nm depth with a 50 nm square nanopore with rounded corners in the base. A gold 3D-structured membrane containing these sized microcavities with the integrated nanopore was successfully fabricated and ‘proof of concept’ Raman scattering experiments are described.
nanopore, polymer sphere, gold membrane, plasmons, sensing, SERS
1-8
Oo, S.Z.
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Silva, G.
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Carpignano, F.
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Noual, A.
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Pechstedt, K.
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Mateos, L.
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Grant-Jacob, J.A.
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Brocklesby, W.S.
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Horak, P.
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Charlton, M.
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Boden, S.A.
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Melvin, Tracy
fd87f5eb-2bb9-48fa-b7be-7100ace9c50f
Oo, S.Z.
6495f6da-8f17-4484-98fb-6151b4efbd9a
Silva, G.
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Carpignano, F.
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Noual, A.
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Pechstedt, K.
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Mateos, L.
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Grant-Jacob, J.A.
c5d144d8-3c43-4195-8e80-edd96bfda91b
Brocklesby, W.S.
c53ca2f6-db65-4e19-ad00-eebeb2e6de67
Horak, P.
520489b5-ccc7-4d29-bb30-c1e36436ea03
Charlton, M.
fcf86ab0-8f34-411a-b576-4f684e51e274
Boden, S.A.
83976b65-e90f-42d1-9a01-fe9cfc571bf8
Melvin, Tracy
fd87f5eb-2bb9-48fa-b7be-7100ace9c50f
Oo, S.Z., Silva, G., Carpignano, F., Noual, A., Pechstedt, K., Mateos, L., Grant-Jacob, J.A., Brocklesby, W.S., Horak, P., Charlton, M., Boden, S.A. and Melvin, Tracy
(2016)
A nanoporous gold membrane for sensing applications.
Sensing and Bio-Sensing Research, .
(doi:10.1016/j.sbsr.2016.01.001).
Abstract
Design and fabrication of three-dimensionally structured, gold membranes containing hexagonally close-packed microcavities with nanopores in the base, are described. Our aim is to create a nanoporous structure with localized enhancement of the fluorescence or Raman scattering at, and in the nanopore when excited with light of approximately 600 nm, with a view to provide sensitive detection of biomolecules. A range of geometries of the nanopore integrated into hexagonally close-packed assemblies of gold micro-cavities was first evaluated theoretically. The optimal size and shape of the nanopore in a single microcavity were then considered to provide the highest localized plasmon enhancement (of fluorescence or Raman scattering) at the very center of the nanopore for a bioanalyte traversing through. The optimized design was established to be a 1200 nm diameter cavity of 600 nm depth with a 50 nm square nanopore with rounded corners in the base. A gold 3D-structured membrane containing these sized microcavities with the integrated nanopore was successfully fabricated and ‘proof of concept’ Raman scattering experiments are described.
Other
1-s2.0-S2214180416300022-main.pdf__tid=7ef26b6c-d4cd-11e5-9e60-00000aacb35f&acdnat=1455641656_dd84c1d009ecb04cca676883e7dafea9
- Accepted Manuscript
More information
Accepted/In Press date: 2 January 2016
e-pub ahead of print date: 11 January 2016
Keywords:
nanopore, polymer sphere, gold membrane, plasmons, sensing, SERS
Organisations:
Optoelectronics Research Centre, Electronics & Computer Science
Identifiers
Local EPrints ID: 387913
URI: http://eprints.soton.ac.uk/id/eprint/387913
ISSN: 2214-1804
PURE UUID: ba352c0c-42d3-43dd-88f9-0c53171676e8
Catalogue record
Date deposited: 16 Feb 2016 16:55
Last modified: 15 Mar 2024 03:37
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Contributors
Author:
S.Z. Oo
Author:
G. Silva
Author:
F. Carpignano
Author:
A. Noual
Author:
K. Pechstedt
Author:
L. Mateos
Author:
M. Charlton
Author:
S.A. Boden
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